What causes depression

There are so many things which have the power of causing the problem of depression for people. Some people start suffering from depression as a result of being abused all their lives.
 
Abuse is one of the main reason for depression. It brings with it some of its friends such as anxiety, pain, grief and regrets. These are what brings about depression eating deep in someone.
 
I know this thread is old, but I'd like to chip in what I believe can contribute to depression. Sometimes things that we don't expect to happen to us can happen out of the blue, and as a result, depression can set in.
 
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